Supplementary Materials

Supplementary Materials for:

Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization

Yuxiao Wang, Huawei He, Nishi Srivastava, Sheikh Vikarunnessa, Yong-bin Chen, Jin Jiang, Christopher W. Cowan, Xuewu Zhang*

*To whom correspondence should be addressed. E-mail: xuewu.zhang{at}utsouthwestern.edu

This PDF file includes:

  • Fig. S1. HPLC-based assay for plexin RapGAP activity.
  • Fig. S2. The RapGAP activity of plexinscyto is stimulated by induced dimerization.
  • Fig. S3. GST-RalGDS pull-down assays for plexin RapGAP activity in cells.
  • Fig. S4. Crystal structure of the PlexinA1cyto-Rac1 complex.

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Citation: Y. Wang, H. He, N. Srivastava, S. Vikarunnessa, Y. Chen, J. Jiang, C. W. Cowan, X. Zhang, Plexins Are GTPase-Activating Proteins for Rap and Are Activated by Induced Dimerization. Sci. Signal. 5, ra6 (2012).

© 2012 American Association for the Advancement of Science