Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist
William S. Bowen, Laurie A. Minns, David A. Johnson, Thomas C. Mitchell, Melinda M. Hutton, Jay T. Evans*
*To whom correspondence should be addressed. E-mail:
This PDF file includes:
- Fig. S1. Comparison of the production of MyD88- and TRIF-dependent cytokines and chemokines by human monocytes treated with CRX-527, CRX-547, Re595 LPS, or sMLA.
- Fig. S2. CRX-547 stimulates the production of lower amounts of IL-1β by human
PBMCs than does CRX-527.
Format: Adobe Acrobat PDF
Size: 300 KB
Citation: W. S. Bowen, L. A. Minns, D. A. Johnson, T. C. Mitchell, M. M. Hutton, J. T. Evans, Selective TRIF-Dependent Signaling by a Synthetic Toll-Like Receptor 4 Agonist. Sci. Signal. 5, ra13 (2012).