Supplementary Materials

Supplementary Materials for:

Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell Proliferation

Céline Delloye-Bourgeois, David Goldschneider, Andrea Paradisi, Gabriel Therizols, Stéphane Belin, Sabine Hacot, Manuel Rosa-Calatrava, Jean-Yves Scoazec, Jean-Jacques Diaz, Agnès Bernet, Patrick Mehlen*

*To whom correspondence should be addressed. E-mail: patrick.mehlen{at}lyon.unicancer.fr

This PDF file includes:

  • Fig. S1. Depletion of ΔN-netrin-1 affects B23 localization within the nucleolus in IMR32 cells.
  • Fig. S2. Depletion of ΔN-netrin-1 affects B23 localization in the nucleolus in H358 cells.
  • Fig. S3. Netrin-1 colocalizes with B23 and nucleolin in the nucleolus.
  • Fig. S4. Characterization of the netrin-1 alternative promoter and ΔN-netrin-1.
  • Fig. S5. ΔN-netrin-1 specifically associates with ribosomal DNA.
  • Fig. S6. ΔN-netrin-1 promotes ribosome biogenesis.
  • Fig. S7. Nucleolar ΔN-netrin-1 promotes cell proliferation.

[Download PDF]

Technical Details

Format: Adobe Acrobat PDF

Size:608 KB


Citation: C. Delloye-Bourgeois, D. Goldschneider, A. Paradisi, G. Therizols, S. Belin, S. Hacot, M. Rosa-Calatrava, J.-Y. Scoazec, J.-J. Diaz, A. Bernet, P. Mehlen, Nucleolar Localization of a Netrin-1 Isoform Enhances Tumor Cell Proliferation. Sci. Signal. 5, ra57 (2012).

© 2012 American Association for the Advancement of Science