Supplementary Materials

Supplementary Materials for:

KCNQ1, KCNE2, and Na+-Coupled Solute Transporters Form Reciprocally Regulating Complexes That Affect Neuronal Excitability

Geoffrey W. Abbott,* Kwok-Keung Tai, Daniel L. Neverisky, Alex Hansler, Zhaoyang Hu, Torsten K. Roepke, Daniel J. Lerner, Qiuying Chen, Li Liu, Bojana Zupan, Miklos Toth, Robin Haynes, Xiaoping Huang, Didem Demirbas, Roberto Buccafusca, Steven S. Gross, Vikram A. Kanda, Gerard T. Berry

*Corresponding author. E-mail: abbottg@uci.edu

This PDF file includes:

  • Fig. S1. Mouse motor function and activity assays.
  • Fig. S2. Kcne2 deletion alters choroid plexus epithelium cell size and shape.
  • Fig. S3. SMIT1, NKCC1, and KCNQ1 expression in choroid plexus and kidney.
  • Fig. S4. KCNQ1 function with and without transporter coexpression.
  • Fig. S5. Functional effects of SMIT2 interaction with KCNQ1-KCNE2.
  • Legend for table S1

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Technical Details

Format: Adobe Acrobat PDF

Size: 1.42 MB

Other Supplementary Material for this manuscript includes the following:

  • Table S1 (Microsoft Excel format). CSF mass spectrometry.

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Citation: G. W. Abbott, K.-K. Tai, D. L. Neverisky, A. Hansler, Z. Hu, T. K. Roepke, D. J. Lerner, Q. Chen, L. Liu, B. Zupan, M. Toth, R. Haynes, X. Huang, D. Demirbas, R. Buccafusca, S. S. Gross, V. A. Kanda, G. T. Berry, KCNQ1, KCNE2, and Na+-Coupled Solute Transporters Form Reciprocally Regulating Complexes That Affect Neuronal Excitability. Sci. Signal. 7, ra22 (2014).

© 2014 American Association for the Advancement of Science