Supplementary Materials

Supplementary Materials for:

Intronic miR-3151 Within BAALC Drives Leukemogenesis by Deregulating the TP53 Pathway

Ann-Kathrin Eisfeld, Sebastian Schwind, Ravi Patel, Xiaomeng Huang, Ramasamy Santhanam, Christopher J. Walker, Joseph Markowitz, Kevin W. Hoag, Tiina M. Jarvinen, Benjamin Leffel, Danilo Perrotti, William E. Carson III, Guido Marcucci, Clara D. Bloomfield, Albert de la Chapelle*

*Corresponding author. E-mail: albert.delachapelle@osumc.edu

This PDF file includes:

  • Fig. S1. Effects of miR-3151 on TP53 abundance in three AML patients.
  • Fig. S2. The abundance of miR-3151 regulates caspase 3 cleavage.
  • Fig. S3. Flow cytometric determination of CD45 abundance in the peripheral blood of NSG mice.
  • Fig. S4. Confirmation of effective knockdown of SP1, NF-κB, and TP53.
  • Table S1. Predicted transcription factor bindings to TSS-3151 and TSS-BAALC.
  • Table S2. Primer sequences for overexpression constructs.
  • Table S3. Primer sequences for luciferase constructs.
  • Table S4. Oligonucleotide sequences for EMSAs.

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Citation: A.-K. Eisfeld, S. Schwind, R. Patel, X. Huang, R. Santhanam, C. J. Walker, J. Markowitz, K. W. Hoag, T. M. Jarvinen, B. Leffel, D. Perrotti, W. E. Carson III, G. Marcucci, C. D. Bloomfield, A. de la Chapelle, Intronic miR-3151 Within BAALC Drives Leukemogenesis by Deregulating the TP53 Pathway. Sci. Signal. 7, ra36 (2014).

© 2014 American Association for the Advancement of Science