Supplementary Materials

Supplementary Materials for:

PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer

Leslie Ann Caromile, Kristina Dortche, M. Mamunur Rahman, Christina L.Grant, Christopher Stoddard, Fernando A. Ferrer, Linda H. Shapiro*

*Corresponding author. Email: lshapiro{at}uchc.edu

This PDF file includes:

  • Fig. S1. CRISPR knockout of PSMA in 22RV1 cells.
  • Fig. S2. CRISPR knockout of PSMA in TRAMP-C1 cells.
  • Fig. S3. PSMA knockdown increases the phosphorylation of ERK1/2 and decreases that of PDK in TRAMP-C1 cells.
  • Fig. S4. Cotransfection of TRAMP-C1 cells with FITC and PSMA blocking peptide.
  • Data file S1. R script document for analysis of GEO data set GSE32571.

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Citation: L. A. Caromile, K. Dortche, M. M. Rahman, C. L. Grant, C. Stoddard, F. A. Ferrer, L. H. Shapiro, PSMA redirects cell survival signaling from the MAPK to the PI3K-AKT pathways to promote the progression of prostate cancer. Sci. Signal. 10, eaag3326 (2017).

© 2017 American Association for the Advancement of Science