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Resetting the Circadian Clock by Social Experience in Drosophila melanogaster

Science, 6 December 2002
Vol. 298, Issue 5600, p. 2010-2012
DOI: 10.1126/science.1076008

Resetting the Circadian Clock by Social Experience in Drosophila melanogaster

  1. Joel D. Levine1,
  2. Pablo Funes1,2,
  3. Harold B. Dowse3,
  4. Jeffrey C. Hall1,*
  1. 1 Department of Biology, Brandeis University, Waltham, MA 02454, USA.
  2. 2 Icosystem Corporation, 10 Fawcett Street, Cambridge, MA, 02138, USA.
  3. 3 Department of Biological Sciences and Department of Mathematics and Statistics, University of Maine, Orono, ME 04469, USA.


Circadian clocks are influenced by social interactions in a variety of species, but little is known about the sensory mechanisms underlying these effects. We investigated whether social cues could reset circadian rhythms in Drosophila melanogasterby addressing two questions: Is there a social influence on circadian timing? If so, then how is that influence communicated? The experiments show that in a social context Drosophilatransmit and receive cues that influence circadian time and that these cues are likely olfactory.

  • * To whom correspondence should be addressed. E-mail: hall{at}

  • Received for publication 11 July 2002.
  • Accepted for publication 17 October 2002.


J. D. Levine, P. Funes, H. B. Dowse, and J. C. Hall, Resetting the Circadian Clock by Social Experience in Drosophila melanogaster. Science 298, 2010-2012 (2002).

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