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Nancy R. Gough
18 March 2008: ec97.
The M2 isoform of pyruvate kinase, which appears to be required for tumorigenesis, is regulated by interaction with tyrosine-phosphorylated peptides. Abstract »  
L. Bryan Ray
18 March 2008: ec98.
The unfolded protein response of the endoplasmic reticulum links signaling pathways controlling metabolism and cell survival. Abstract »  
Annalisa VanHook
18 March 2008: ec99.
PKC{delta} and Abl cooperate to communicate ER stress to the mitochondria. Abstract »  
John F. Foley
18 March 2008: ec100.
Two studies identify Scalloped as the transcription factor that activates the expression of genes antagonized by the Hippo pathway. Abstract »  
Elizabeth M. Adler
18 March 2008: ec101.
BAFF promotes B cell survival by stimulating TRAF3 depletion. Abstract »  
John F. Foley
18 March 2008: ec102.
The dynein regulator Nudel facilitates migration by helping to keep Cdc42 active at the front of the cell. Abstract »  
Annalisa VanHook
18 March 2008: ec103.
A screen identifies MMP3 as a transcriptional regulator. Abstract »  
L. Bryan Ray
18 March 2008: ec104.
A yeast signaling pathway acquires new regulatory properties (such as adaptation) when additional protein-protein interaction sites are engineered into a scaffolding protein. Abstract »  
Peter Stern
18 March 2008: ec105.
Stronger synapses induced by calcium currents are responsible for working memory rather than the more metabolically expensive action potential firing, as had been thought. Abstract »  
Paula A. Kiberstis
18 March 2008: ec106.
A drug that inhibits a neural signaling pathway linked to behavioral stress may be a useful therapy in preventing relapse in alcoholics. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882