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Editors' Choice

Nancy R. Gough
15 April 2008: ec129.
Bacteria interfere with Toll-like receptor signaling by secreting proteins with TIR domains that compete with the MyD88 adaptor. Abstract »  
L. Bryan Ray
15 April 2008: ec130.
Endothelin derived from blood vessels helps direct sympathetic neurons to their target organs. Abstract »  
Pamela J. Hines
15 April 2008: ec131.
In mice, axons carrying signals from spinal cord to muscle are kept separate from those going in the opposite direction by ephrin signaling between them. Abstract »  
Elizabeth M. Adler
15 April 2008: ec132.
AKAP121 degradation leads to decreased mitochondrial metabolism under hypoxic conditions. Abstract »  
Annalisa M. VanHook
15 April 2008: ec133.
Precise control of adhesive properties is essential for collective migration. Abstract »  
Nancy R. Gough
15 April 2008: ec134.
In the nucleus, Bcl2 interacts with apurinic/apyrimidinic endonuclease 1 (APE1) to inhibit DNA repair. Abstract »  
Paula A. Kiberstis
15 April 2008: ec135.
A drug that triggers the pathway that cancer cells use to avoid death can protect healthy cells from the harmful effects of radiation treatment. Abstract »  
Peter Stern
15 April 2008: ec136.
Desensitized glutamate receptors are exchanged for functional ones through lateral movement within membranes to help maintain fast excitatory neurotransmission. Abstract »  

 

Journal Club

Ti-Fei Yuan
15 April 2008: jc1.
GABA regulates neurogenesis in various circumstances. Abstract »   Full Text »   PDF »  

 

Reviews

Martin Lackmann and Andrew W. Boyd
15 April 2008: re2.
Eph receptors and their ephrin ligands coordinate cell-positioning programs during development and oncogenesis. Gloss »   Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882