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Elizabeth M. Adler
13 May 2008: ec172.
Membrane microvesicles provide a mechanism for horizontal transfer of the transformed phenotype. Abstract »  
John F. Foley
13 May 2008: ec173.
The phosphatase Prl-3, previously associated with metastasis, is encoded by a p53-inducible gene that has opposing effects on the cell cycle depending on its abundance. Abstract »  
Nancy R. Gough
13 May 2008: ec174.
Mice null for the gene that encodes prion protein show altered electrophysiological properties of NMDA-type glutamate receptors. Abstract »  
Annalisa M. VanHook
13 May 2008: ec175.
Cytoplasmic proteins can be activated by mechanical stress faster than by pathways that rely on diffusion of intracellular molecules. Abstract »  
Elizabeth M. Adler
13 May 2008: ec176.
Live-cell imaging of Rab5 activation during phagocytosis enables development of a model of its activation through the delivery by microtubules of Gapex-5. Abstract »  
Annalisa M. VanHook
13 May 2008: ec177.
The renin-angiotensin system regulates fat accumulation by altering global metabolism. Abstract »  
L. Bryan Ray
13 May 2008: ec178.
An olfactory neuron in Caenorhabditis elegans also senses the ambient temperature and is necessary for worms’ propensity to seek out the temperature at which they were raised. Abstract »  
L. Bryan Ray
13 May 2008: ec179.
A systematic, functional screen of extracellular proteins in yeast identified a previously unknown receptor-ligand pair: the cytokine interleukin-34 and its receptor. Abstract »   Correction »  
L. Bryan Ray
13 May 2008: ec180.
Activation of a heat-sensitive sensory neuron in the worm Caenorhabditis elegans unexpectedly triggers a heat-shock response throughout the animal. Abstract »  



Rajat Varma
13 May 2008: pe21.
Multiple models compete to explain T cell receptor activation. Abstract »   Full Text »   PDF »  



Alan R. Kay and Katalin Tóth
13 May 2008: re3.
Experiments with metal chelators and genetically modified mice provide the best means for determining whether zinc acts as a regulator of synaptic activity. Gloss »   Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882