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Cover Figure

COVER This week's issue features a Perspective that discusses how the von Hippel-Lindau tumor suppressor protein (pVHL) controls both transcription-dependent and transcription-independent cellular processes. The image shows the structure of pVHL (blue) in a complex with the proteins Elongins B and C and is based on PDB structure 1VCB. [Image: Chris Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882