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Cover Figure

COVER This week's issue features a Perspective that discusses the role of Sonic hedgehog (Shh) in promoting the proliferation of mesenchymal cells that give rise to digits in the developing limb. The image shows the anterior and posterior digits that form in the chick limb. [Image: Craig Nicol, MRC Human Genetics Unit, Western General Hospital, Edinburgh, UK]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882