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Cover Figure

COVER In this week's issue, Science Signaling launches the publication of primary research articles. The first Research Article describes the importance of the extracellular calcium-sensing receptor (CaSR) to embryonic and postnatal skeletal development. The image shows the skeletons of control, heterozygous, and homozygous knockout mice for Casr in parathyroid cells. [Image: Wenhan Chang, UCSF]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882