28 October 2008
Vol 1, Issue 43

About The Cover

Cover image expansion

COVER This week's issue features a Research Article that shows that signaling mediated by the adaptor protein DAP12 is essential for macrophages to fuse and form multinucleated giant cells, which are a hallmark of granulomatous inflammation. The cover shows macrophages that have fused (yellow). [Image: Laura Helming, Technical University of Munich, Germany]