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Cover Figure

COVER This week's issue features a Perspective on the possible ligand-independent activities of peroxisome proliferator–activated receptor {gamma} (PPAR{gamma}). The image shows a ribbon diagram of the structure of PPAR{gamma} with the ligand-binding pocket indicated. [Image: Millard Lambert, GlaxoSmithKline, Research Triangle Park, NC 27709]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882