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Editors' Choice

Nancy R. Gough
13 January 2009: ec10.
Small molecules that trigger potassium leakage from bacteria lead to biofilm formation. Abstract »  
John F. Foley
13 January 2009: ec11.
Mouse bone marrow–derived mesenchymal stem cells change the cytokine profile of macrophages during sepsis, leading to increased survival. Abstract »  
Elizabeth M. Adler
13 January 2009: ec12.
LKB1-AMPK signaling enhances survival in dauer by limiting depletion of lipid stores. Abstract »  
Wei Wong
13 January 2009: ec13.
Subcellular location and cell cycle status determine whether a scaffold protein is degraded by the proteasome. Abstract »  
L. Bryan Ray
13 January 2009: ec14.
An enzyme that deacetylates histones in the nucleus also functions in the cytoplasm to promote the survival of retinal neurons in mice. Abstract »  
Laura M. Zahn
13 January 2009: ec15.
A gene that controls male floral development in maize is involved in synthesis of a hormone that suppresses female organ development. Abstract »  
L. Bryan Ray
13 January 2009: ec16.
Signals from a cancer-associated receptor that activate a key pathway in the immune system are modulated by its binding to a stress-responsive transcription factor. Abstract »  
Stella M. Hurtley
13 January 2009: ec17.
A GI-active pathogen destroys intestinal cells, in part by improperly modifying a host signaling protein, causing loss of cell shape and contributing to cell death. Abstract »  
L. Bryan Ray
13 January 2009: ec18.
Receptors for the plant hormone abscisic acid have built-in G protein modules. Abstract »  

 

Podcasts

John D. Scott, Wei Wong, and Annalisa M. VanHook
13 January 2009: pc1.
The scaffold protein mAKAP localizes factors important for the cellular response to hypoxia. Abstract »   Full Text »   Podcast »  

 

Perspectives

Yingzi Yang
13 January 2009: pe3.
Signaling gradients coordinately regulate proliferation and cell fate determination in the developing limb. Abstract »   Full Text »   PDF »  

 

Errata

 
13 January 2009: er1.
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882