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Editors' Choice

Annalisa M. VanHook
20 January 2009: ec19.
Signaling through metabotropic glutamate receptors affects the nematode starvation response. Abstract »  
Elizabeth M. Adler
20 January 2009: ec20.
Activation of TLR4 signaling by saturated fatty acids plays an important role in the hypothalamic response to a high-fat diet. Abstract »  
L. Bryan Ray
20 January 2009: ec21.
Intramembrane proteolysis enhances signaling by interleukin-1 receptor type 1. Abstract »  
Wei Wong
20 January 2009: ec22.
Culture environment and presence of extracellular matrix attachments synergize to regulate the angiogenic signals that tumor cells release. Abstract »  
Pamela J. Hines
20 January 2009: ec23.
A protein cue guides the formation of bundles of nerve fibers that connect the cerebral hemispheres. Abstract »  
Helen Pickersgill
20 January 2009: ec24.
A persistence factor similar to a eukaryotic kinase regulates bacterial dormancy and contributes to antibiotic resistance in E. coli. Abstract »  
Helen Pickersgill
20 January 2009: ec25.
Mutations in neuropeptide receptors prevent nematode worms from swimming away to avoid bacterial pathogens. Abstract »  
Wei Wong
20 January 2009: ec26.
A steroid hormone and its nuclear receptor regulate dauer formation and infectivity in larvae from different nematode species. Abstract »  

 

Connections Map Overviews

Avi Ma'ayan, Sherry L. Jenkins, Alexander Barash, and Ravi Iyengar
20 January 2009: cm1.
Neurite outgrowth can be stimulated by G protein-coupled receptors that signal through G{alpha}i and G{alpha}o proteins. Abstract »   Full Text »   PDF »   Pathway »  

 

Perspectives

Pamela A. Lochhead
20 January 2009: pe4.
The mechanisms by which kinases activate themselves are still emerging. Abstract »   Full Text »   PDF »  

 

Protocols

Shakiba Jalal, Ryan Arsenault, Andrew A. Potter, Lorne A. Babiuk, Philip J. Griebel, and Scott Napper
20 January 2009: pl1.
Marrying bioinformatics and phosphorylation assays enables the empirical analysis of kinomes of multiple species. Abstract »   Full Text »   PDF »   Supplementary Materials »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882