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Editors' Choice

Nancy R. Gough
19 May 2009: ec165.
The fatty acid oleoylethanolamide, which is produced in response to feeding, enhances rodent memory consolidation. Abstract »  
L. Bryan Ray
19 May 2009: ec166.
The sirtuin deacetylases are implicated in long-term changes in gene expression associated with chronic exposure to cocaine. Abstract »  
Peter Stern
19 May 2009: ec167.
The protein Vesl-1S fulfills the synaptic tagging hypothesis for the maintenance of input-specific action of neuronal networks. Abstract »  
Elizabeth M. Adler
19 May 2009: ec168.
EGFR autophosphorylation affects ligand-binding affinity. Abstract »  
Annalisa M. VanHook
19 May 2009: ec169.
ERKs 1 and 2 are required in granulosa cells for oocyte maturation. Abstract »  
Pamela Hines
19 May 2009: ec170.
A single receptor in Drosophila is involved in two molecular strategies that coordinate axon guidance. Abstract »  



Elena Oancea and Annalisa M. VanHook
19 May 2009: pc9.
TRPM1 is a cation channel found on vesicular membranes and associated with melanin content in melanocytes. Abstract »   Full Text »   Podcast »  


Research Articles

Robert C. Hsueh, Madhusudan Natarajan, Iain Fraser, Blake Pond, Jamie Liu, Susanne Mumby, Heping Han, Lily I. Jiang, Melvin I. Simon, Ronald Taussig, and Paul C. Sternweis
19 May 2009: ra22.
Despite being exposed to multiple ligands, a macrophage cell line exhibits a surprisingly limited number of responses. Editor's Summary »   Abstract »   Full Text »   PDF »  
Ingo Lange, Shinichiro Yamamoto, Santiago Partida-Sanchez, Yasuo Mori, Andrea Fleig, and Reinhold Penner
19 May 2009: ra23.
TRPM2-mediated Ca2+ release from lysosomal stores contributes to pancreatic β cell death in response to oxidative stress. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Susan Mackem and Mark Lewandoski
19 May 2009: pe33.
Gremlin links slow and fast signaling feedback loops, which contributes to robust regulation of mouse limb patterning. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882