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Editors' Choice

John F. Foley
23 June 2009: ec204.
CD44-dependent proliferation of gastric cancer cells is mediated by acetylated, but unphosphorylated, STAT3. Abstract »  
Wei Wong
23 June 2009: ec205.
The ERK pathway promotes phosphorylation of lysyl-tRNA synthetase and its nuclear translocation during mast cell activation. Abstract »  
Elizabeth M. Adler
23 June 2009: ec206.
The CCR7 chemokine receptor is critical for invasion of the central nervous system by T cell acute lymphoblastic leukemia cells. Abstract »  
Nancy R. Gough
23 June 2009: ec207.
Complex formation, protein processing, and biosynthesis contribute to the rapid and long-term responses to stimuli that activate NF-{kappa}B. Abstract »  
Stella M. Hurtley
23 June 2009: ec208.
Live-cell microscopy reveals local translation during long-term facilitation of Aplysia sensory-motor synapses. Abstract »  
Elizabeth M. Adler
23 June 2009: ec209.
H2O2 represents a critical signal for recruiting leukocytes to injury sites. Abstract »  
Kristen Mueller
23 June 2009: ec210.
The cytokine interleukin-21 has a profound impact on virus-specific T cell responses to chronic infections in mice. Abstract »  
Valda Vinson
23 June 2009: ec211.
The architecture of a membrane protein channel helps explain how Escherichia coli survive the acidic conditions of the stomach. Abstract »  

 

Podcasts

Andre Levchenko and Annalisa M. VanHook
23 June 2009: pc11.
A microfluidic device enables high-throughput analysis of signaling in individual cells. Abstract »   Full Text »   Podcast »  

 

Research Articles

Helen Oi-Lam Cheung, Xiaoyun Zhang, Ana Ribeiro, Rong Mo, Shigeru Makino, Vijitha Puviindran, Kelvin K. L. Law, James Briscoe, and Chi-chung Hui
23 June 2009: ra29.
Kif7 may be the functional equivalent of the Drosophila kinesin-like protein Costal2. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Thomas Gruber, Natascha Hermann-Kleiter, Reinhard Hinterleitner, Friedrich Fresser, Rainer Schneider, Günther Gastl, Josef M. Penninger, and Gottfried Baier
23 June 2009: ra30.
PKC-{theta} triggers the degradation of Cbl-b that is necessary for a full immune response in T cells. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  

 

Perspectives

M. Lienhard Schmitz
23 June 2009: pe38.
Degradation of the ubiquitin E3 ligase Cbl-b in response to T cell costimulation depends on PKC-{theta}. Abstract »   Full Text »   PDF »  
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