04 August 2009
Vol 2, Issue 82

About The Cover

Cover image expansion

Online Cover This week's issue features a Research Article showing that the protein kinase Akt1 regulates postnatal reparative angiogenesis largely through phosphorylation of endothelial nitric oxide synthase (eNOS). The image depicts angiogenic endothelium from a line of mice that lack Akt1 and carry a mutation in eNOS that mimics its phosphorylation by Akt1. [Image: Takahisa Murata, University of Tokyo, and Jun Yu, Yale University]