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Editors' Choice

Wei Wong
4 August 2009: ec257.
CRTC2 participates in transcriptional responses required for ER stress responses and gluconeogenesis. Abstract »  
Elizabeth M. Adler
4 August 2009: ec258.
Par-4 functions extracellularly as well as intracellularly to elicit apoptosis in malignant cells. Abstract »  
Nancy R. Gough
4 August 2009: ec259.
A set of antagonists that block both intracellular and cell surface quorum-sensing receptors protects worms against bacterial infection. Abstract »  
Kristen Mueller
4 August 2009: ec260.
Mouse immune systems interact to ensure tolerance to nonpathogenic bacteria in the gut. Abstract »  
John F. Foley
4 August 2009: ec261.
Presynaptic, but not postsynaptic, presenilins enhance neurotransmitter release and long-term potentiation at the hippocampal CA3-CA1 synapse. Abstract »  
Stella M. Hurtley
4 August 2009: ec262.
The mouse olfactory topographic neural map is self-organized by interactions between axons, not directed by the target. Abstract »  
L. Bryan Ray
4 August 2009: ec263.
A drug used to enhance insulin secretion in diabetes has a previously unrecognized protein target. Abstract »  


Research Articles

Michael Schleicher, Jun Yu, Takahisa Murata, Berhad Derakhshan, Dimitriy Atochin, Li Qian, Satoshi Kashiwagi, Annarita Di Lorenzo, Kenneth D. Harrison, Paul L. Huang, and William C. Sessa
4 August 2009: ra41.
Akt mediates postnatal angiogenesis through eNOS signaling. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Joel S. Bader
4 August 2009: pe48.
Secrets of the yeast MAPK pathways continue to be revealed. Abstract »   Full Text »   PDF »   Preview PDF »  


Meeting Reports

Ronald N. Margolis, David D. Moore, Timothy M. Willson, and R. Kip Guy
4 August 2009: mr5.
An NIH-sponsored workshop focused on innovative chemical methods for probing and modulating nuclear receptor pathways. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882