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Cover Figure

ONLINE COVER This week's issue features a Research Article showing that the protein kinase Akt1 regulates postnatal reparative angiogenesis largely through phosphorylation of endothelial nitric oxide synthase (eNOS). The image depicts angiogenic endothelium from a line of mice that lack Akt1 and carry a mutation in eNOS that mimics its phosphorylation by Akt1. [Image: Takahisa Murata, University of Tokyo, and Jun Yu, Yale University]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882