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Editors' Choice

Annalisa M. VanHook
22 September 2009: ec309.
Related receptor-like tyrosine kinases are differentially required in male and female gametophytes for fertilization. Abstract »  
John F. Foley
22 September 2009: ec310.
A viral protein inhibits the function of a K+ channel to prevent infected cells from undergoing apoptosis. Abstract »  
Nancy R. Gough
22 September 2009: ec311.
A mouse cancer model reveals genes that, when mutated, promote drug resistance in leukemias caused by excessive signaling through the Ras-MAPK pathway. Abstract »  
Paula A. Kiberstis
22 September 2009: ec312.
Glucose deprivation can drive the acquisition of certain oncogenic mutations in human cancer cells. Abstract »  
Wei Wong
22 September 2009: ec313.
Neutralization of vascular endothelial growth factor by its soluble receptor provides guidance cues during sprouting angiogenesis. Abstract »  
Stella M. Hurtley
22 September 2009: ec314.
Bacteria produce D-amino acids to regulate their cell wall composition, structure, amount, and strength. Abstract »  
Peter R. Stern
22 September 2009: ec315.
Itch, but not pain sensation, is abolished by selective ablation of a small subpopulation of spinal neurons. Abstract »  
L. Bryan Ray
22 September 2009: ec316.
Inhibitory effects of bone morphogenetic protein 15 may explain effects on development and adult infertility. Abstract »  

 

Research Articles

Carmen Finger, Claudia Escher, and Dirk Schneider
22 September 2009: ra56.
The transmembrane domain of any of the 58 human receptor tyrosine kinases is sufficient to mediate dimerization. Editor's Summary »   Abstract »   Full Text »   PDF »  
Susana Llanos, Ana Cuadrado, and Manuel Serrano
22 September 2009: ra57.
The kinase MSK2 inhibits p53 transcriptional activity at a subset of promoters through a kinase-independent mechanism. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  

 

Perspectives

Erik H. J. Danen
22 September 2009: pe58.
A proteomics analysis of integrin-associated complexes establishes an unexpected connection to cell migration. Abstract »   Full Text »   PDF »  
Philip D. Stahl and Marisa J. Wainszelbaum
22 September 2009: pe59.
Analysis of human-specific genes may reveal, at the molecular level, what makes humans human. Abstract »   Full Text »   PDF »  

 

Errata

 
22 September 2009: er7.
Full Text »   PDF »  
 
22 September 2009: er8.
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882