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Cover Figure

ONLINE COVER This week's issue features a Focus Issue that highlights how changes in redox state and reactive species produced by reduction-oxidation reactions trigger changes in cellular behavior. In some cases, these signals couple cellular metabolic state to changes in gene expression. The image is an artist's depiction of a nucleus (the site of gene expression) and mitochondria (the site of energy production and oxygen utilization) within a cell. [Image: Chris Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882