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Editors' Choice

Elizabeth M. Adler
3 November 2009: ec352.
Mast cell–derived particles provide a mechanism for the safe transport of signaling factors from inflamed tissues to the draining lymph nodes. Abstract »  
Nancy R. Gough
3 November 2009: ec353.
Endogenous pseudophosphatases involved in the transition from oocyte to zygote inhibit kinase activity by "substrate trapping." Abstract »  
John F. Foley
3 November 2009: ec354.
The ubiquitin-conjugating enzyme Ubc5 is required for the activation of interferon regulatory factor 3 during the mitochondrial antiviral response. Abstract »  
Helen Pickersgill
3 November 2009: ec355.
A vertebrate hemerythrin domain in an E3 ubiquitin ligase complex senses and regulates cellular iron levels. Abstract »  
Elizabeth M. Adler
3 November 2009: ec356.
Some odorants can activate nuclear estrogen receptors, as well as cell surface odor receptors. Abstract »  


Research Articles

Amir M. Ashique, Youngshik Choe, Mattias Karlen, Scott R. May, Khanhky Phamluong, Mark J. Solloway, Johan Ericson, and Andrew S. Peterson
3 November 2009: ra70.
Rfx4 regulates the formation of primary cilia, thereby playing a crucial role in central nervous system development. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  
Matthias Christen, Lisette H. Coye, Jill S. Hontz, Doris L. LaRock, Richard A. Pfuetzner, Megha, and Samuel I. Miller
3 November 2009: ra71.
An enzyme essential for the virulence of Salmonella in mammals is activated by the GTP-bound form of RhoA. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  



Sandip Patel and Roberto Docampo
3 November 2009: pe69.
Cationic channels of the TRP melastatin family are involved in pigmentation and oxidative stress responses. Abstract »   Full Text »   PDF »  


Meeting Reports

Giovanni Blandino, Yosef Shaul, Sabrina Strano, Marius Sudol, and Michael Yaffe
3 November 2009: mr6.
Researchers of flies and mammals met to discuss components of the Hippo signaling pathway. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882