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Cover Figure

ONLINE COVER This week's issue features a Focus Issue highlighting the diverse signaling pathways that cells use to sense and respond to stress. The seemingly idyllic image depicts several potential forms of cellular stress, including ultraviolet radiation and heat (from the sun), osmotic stress (from salt water), and nutrient stress (from the potential diet-induced obesity represented by the coconut). [Image: Jupiterimages]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882