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Cover Figure

COVER This week features an Editorial Guide on the Connections Maps cell signaling database, as part of the 2004 annual Cell Signaling issue in Science and Science's STKE. The MAPK cascade appears in various signaling pathways added to the database this year, highlighting the ubiquity of signaling mechanisms that are shared in organisms from yeast to plants to mammals, represented here by the ancient symbol of the mandala. [Image: Julie White and Elizabeth M. Adler, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882