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Cover Figure

COVER This week features a Perspective on the design of small-molecule inhibitors that specifically inhibit binding of selected transcription factors at target genes. The image depicts a bHLH heterodimer transcription factor bound to DNA. [Image: Charles Vinson, NIH]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882