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Cover Figure

COVER This week features a Perspective on the role of E3 ubiquitin ligases in regulating cytokine signaling. The image depicts JAK/STAT regulation through the ubiquitin-proteasome pathway. [Image: Christopher Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882