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Cover Figure

COVER This week features a Review on signaling pathways involved in regulating the response to existing--or anticipated--hypoxia. The image depicts HIFα and a target gene containing a hypoxia-response element. [Image: Christopher Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882