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Cover Figure

COVER This week features an Editorial Guide highlighting the most notable advances in cell signaling research of 2005. The image represents a model of the CaMKII holoenzyme superimposed on a network of signaling molecules. [Image: Christopher Bickel, AAAS. Image of CaMKII reprinted from O. S. Rosenberg et al., Cell 123, 849–860 (2005), with permission from Elsevier.]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882