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Cover Figure

COVER This week features a Perspective on the selective activation of different responses by ligands that preferentially stabilize different conformations of the same receptor. The image depicts ligands binding to two different conformational states of a G protein-coupled receptor. [Image: Christopher Bickel, AAAS]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882