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Perspectives

Judah Folkman
Sci. STKE 26 September 2006: pe35.
p53 inhibits not only tumor cell proliferation and survival but also tumor angiogenesis. Abstract »   Full Text »   PDF »  
Rumyana Karlova and Sacco C. de Vries
Sci. STKE 26 September 2006: pe36.
Plants use plasma membrane receptor complexes to trigger the response to steroid hormones. Abstract »   Full Text »   PDF »  
Robin P. Wharton and Aneel K. Aggarwal
Sci. STKE 26 September 2006: pe37.
How do Puf domain proteins regulate mRNA and what are their targets? Abstract »   Full Text »   PDF »  

 

Editors' Choice

Nancy R. Gough
Sci. STKE 26 September 2006: tw327.
Caspase 1 promotes membrane repair in response to pathogens. Abstract »  
Elizabeth M. Adler
Sci. STKE 26 September 2006: tw328.
Inhibitory cell surface receptor PD-1 is implicated in T cell "exhaustion" during chronic HIV infection. Abstract »  
L. Bryan Ray
Sci. STKE 26 September 2006: tw329.
A disulfide bond acts as a switch in control of blood coagulation. Abstract »  
Nancy R. Gough
Sci. STKE 26 September 2006: tw330.
Myc stimulates IL-1ß secretion to stimulate endothelial cell proliferation and tubulogenesis. Abstract »  
Elizabeth M. Adler
Sci. STKE 26 September 2006: tw331.
DOCK 7 regulates axon formation by means of Op18 regulation of microtubule dynamics. Abstract »  
Nancy R. Gough
Sci. STKE 26 September 2006: tw332.
Oxidative stress and ultraviolet radiation promote phosphorylation of PIP5K, which prevents resynthesis of PI(4,5)P2 and leads to cell death. Abstract »  
Elizabeth M. Adler
Sci. STKE 26 September 2006: tw333.
Activation of cAMP signaling downstream of MC1R elicits eumelanin production and protects against skin damage. Abstract »  
Pamela J. Hines
Sci. STKE 26 September 2006: tw334.
A molecule that is usually thought of as a hallmark of the immune system interacts with a receptor in the brain to limit the plasticity of the visual system during development. Abstract »  
Pamela J. Hines
Sci. STKE 26 September 2006: tw335.
Proteins linked to a particular epilepsy syndrome are found to work together at brain synapses. Abstract »  
Peter Stern
Sci. STKE 26 September 2006: tw336.
The complexity and intensity of social interaction, information gleaned during prior waking, or both stably change sleep patterns in Drosophila. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882