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Perspectives

Peter Vandenabeele, Tom Vanden Berghe, and Nele Festjens
Sci. STKE 24 October 2006: pe44.
In the absence of apoptosis, cells may undergo autophagic or necrotic cell death. Abstract »   Full Text »   PDF »  
Rose Zamoyska
Sci. STKE 24 October 2006: pe45.
Superantigens activate an alternative pathway during T cell activation that involves G{alpha}11 of the Gq family and PLC-beta signaling. Abstract »   Full Text »   PDF »  

 

Editors' Choice

L. Bryan Ray
Sci. STKE 24 October 2006: tw362.
A protein identified as a tumor suppressor controls overall protein synthesis rates through a translation initiation factor, promoting cell proliferation and growth. Abstract »  
L. Bryan Ray
Sci. STKE 24 October 2006: tw363.
Protein degradation may be as important as new protein synthesis in producing long-term changes in synapse function. Abstract »  
Elizabeth M. Adler
Sci. STKE 24 October 2006: tw364.
PGC-1{alpha} plays a critical role in regulating ROS metabolism and may present a target for therapeutic manipulation. Abstract »  
Nancy R. Gough
Sci. STKE 24 October 2006: tw365.
Decreased signaling through PI3K is required for class switch recombination. Abstract »  
Stella M. Hurtley
Sci. STKE 24 October 2006: tw366.
The protein through which HIV infects immune cells normally senses a heat shock protein from mycobacteria to initiate an antibacterial response. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882