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Perspectives

Domingo F. Barber, Maria Alvarado-Kristensson, Ana González-García, Rafael Pulido, and Ana C. Carrera
Sci. STKE 21 November 2006: pe49.
The liver can adapt to loss of p85 by decreasing PTEN activity, thereby restoring insulin sensitivity. Abstract »   Full Text »   PDF »  
Mirko H. H. Schmidt and Ivan Dikic
Sci. STKE 21 November 2006: pe50.
The Cbl E3 ligase can mediate both ubiquitylation and neddylation of the EGFR. Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 21 November 2006: tw392.
Small noncoding RNAs may activate the expression of target genes. Abstract »  
Nancy R. Gough
Sci. STKE 21 November 2006: tw393.
A chemical found in red wine prevents diseases and accelerated aging-associated obesity in mice. Abstract »  
Elizabeth M. Adler
Sci. STKE 21 November 2006: tw394.
Stimulation of a serotonin receptor may underlie the immunosuppressive effects of UV radiation. Abstract »  
L. Bryan Ray
Sci. STKE 21 November 2006: tw395.
Glycogen synthase kinase 3beta undergoes a chaperone-aided switch in specificity toward tyrosine residues. Abstract »  
L. Bryan Ray
Sci. STKE 21 November 2006: tw396.
Splice variants of receptors for the reproductive hormone relaxin reveal new modes of G protein-coupled receptor signaling. Abstract »  
Nancy R. Gough
Sci. STKE 21 November 2006: tw397.
Ras promotes the maximal activation of phosphoinositide 3-kinase in flies and neutrophils. Abstract »  
Stephen Simpson
Sci. STKE 21 November 2006: tw398.
Immune cells in the gut are programmed by other cells in the nearby lymphoid tissue and a vitamin A-related signal to make antibodies that protect against gut pathogens. Abstract »  
Stella M. Hurtley
Sci. STKE 21 November 2006: tw399.
As cells divide during development, daughter cells retain the growth signals received by their parents through equal partitioning of a subpopulation of tagged intracellular vesicles. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882