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Perspectives

Hanna-Mari Pallari and John E. Eriksson
Sci. STKE 19 December 2006: pe53.
Novel roles for intermediate filaments depend on their ability to sequester or act as scaffolds for signaling molecules. Abstract »   Full Text »   PDF »  

 

Reviews

Michael S. Samoilov, Gavin Price, and Adam P. Arkin
Sci. STKE 19 December 2006: re17.
In both single-celled organisms and multicellular organisms, stochastic changes in gene expression lead to different cellular fates. Gloss »   Abstract »   Full Text »   PDF »  

 

Editors' Choice

Pamela J. Hines
Sci. STKE 19 December 2006: tw423.
A burst of maternal oxytocin activates an inhibitory system during labor, thus protecting the neonatal rat brain from injury resulting from oxygen deprivation. Abstract »  
Nancy R. Gough
Sci. STKE 19 December 2006: tw424.
Inhibition of cytohesin activity causes insulin resistance by blocking early steps in insulin signaling. Abstract »  
Elizabeth M. Adler
Sci. STKE 19 December 2006: tw425.
G{alpha}o binds PKA, thereby directing its subcellular localization and regulating its downstream effects. Abstract »  
L. Bryan Ray
Sci. STKE 19 December 2006: tw426.
Ligands may not need to bind directly to receptors to alter receptor signaling. Abstract »  
L. Bryan Ray
Sci. STKE 19 December 2006: tw427.
Human leukocytes amplify a chemoattractant gradient by making their own gradient of other signaling molecules. Abstract »  
Caroline Ash
Sci. STKE 19 December 2006: tw428.
Genetic mapping identifies the proteins that cause toxoplasmosis when injected by the parasite, one of which is a kinase that interferes with the host signaling pathways. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882