13 February 2007
Vol 2007, Issue 373
  • Contents

    • Perspective

    • Editors' Choice

      • A Motor for Netrin Receptors

        The netrin receptors neogenin and DCC interact with and differentially regulate neurite extension through the atypical myosin Myo X.

      • Opening the Nuclear Gates

        Hormones that stimulate Ca2+ signaling may modulate transcription of target genes by regulating nuclear envelope permeability.

      • The Grim Reaper on Autopilot?

        Two cell death-related proteins need to be constantly inhibited by prosurvival proteins to prevent death by default in human cells.

      • Shifting the Balance

        Endocannabinoid-mediated long-term depression in the indirect pathway appears to contribute to striatal control of motor activity.

      • A Receptor for Vitamin A Uptake

        A membrane protein with a previously unknown function binds the carrier protein for vitamin A, causes release of the vitamin, and transports it into cells.

      • Two Wings Good, Four Wings Better

        Moths' antennae detect rotational motion and relay this mechanosensory input to neural centers to maintain stability during flight.

About The Cover

Cover image expansion

COVER This week features a Perspective on glucose regulation of genes that encode proteins involved in photosynthesis. The image depicts formation of a nuclear complex that includes the glycolytic enzyme hexokinase under conditions of excess glucose. [Image: Christopher Bickel, AAAS]