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Lana Bozulic, Pier Jr Morin, Tony Hunter, and Brian A. Hemmings
Sci. STKE 20 February 2007: pe8.
Scientists explore the past, present, and future of protein kinase research in the light of cancer therapy development. Abstract »   Full Text »   PDF »  


Editors' Choice

Elizabeth M. Adler
Sci. STKE 20 February 2007: tw57.
Opposing effects of K+ channels on neuropeptide release may contribute to its activity dependence. Abstract »  
Nancy R. Gough
Sci. STKE 20 February 2007: tw58.
Microarray analysis reveals prosurvival and pro-death transcriptional responses to NMDA receptor activation. Abstract »  
L. Bryan Ray
Sci. STKE 20 February 2007: tw59.
Queen bees may influence workers with a dopamine-like pheromone. Abstract »  
Nancy R. Gough
Sci. STKE 20 February 2007: tw60.
Disrupting the interaction of Patched with Tid1 contributes to squamous cell carcinoma. Abstract »  
Pamela J. Hines
Sci. STKE 20 February 2007: tw61.
Stem cell daughters in the Drosophila intestine can take on one of three identities; this choice is controlled by the activation level of a common developmental receptor. Abstract »  
Stella M. Hurtley
Sci. STKE 20 February 2007: tw62.
A family of virulence factors in bacteria removes a phosphate from a key signaling enzyme in its infected host and thereby interferes with the host's innate immunity. Abstract »  
Stephen Simpson
Sci. STKE 20 February 2007: tw63.
A mouse version of rheumatoid arthritis can be ameliorated by inhibition or elimination of a cell surface adhesion molecule found within joints, suggesting a therapeutic approach for humans. Abstract »  
Stella M. Hurtley
Sci. STKE 20 February 2007: tw64.
In motile cells, actin fibers form integrin-covered protrusions that are poised to interact with surfaces in the cell's search for adhesion sites. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882