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Perspectives

Jörg Stelling
Sci. STKE 6 March 2007: pe9.
The book "An Introduction to Systems Biology" offers a look at the design principles of biological control circuits. Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 6 March 2007: tw73.
Dendritic cells convert vitamin D3 into the active form and thereby direct T cell homing to skin. Abstract »  
Nancy R. Gough
Sci. STKE 6 March 2007: tw74.
Caspase 11 promotes cell migration by participating in regulation of actin dynamics. Abstract »  
L. Bryan Ray
Sci. STKE 6 March 2007: tw75.
The calcium sensor hippocalcin mediates potassium channel activation that protects neurons from hyperexcitability. Abstract »  
Peter Stern
Sci. STKE 6 March 2007: tw76.
In an unusual form of plasticity, certain synapses in rat interneurons are strengthened if presynaptic activity occurs while the postsynaptic cell is at rest or hyperpolarized. Abstract »  
Paula A. Kiberstis
Sci. STKE 6 March 2007: tw77.
A mutation in a key signaling pathway causes both coronary artery disease and a metabolic syndrome, explaining why these disorders are often associated with one another. Abstract »  
Elizabeth M. Adler
Sci. STKE 6 March 2007: tw78.
Orexigenic effects of atypical antipsychotic drugs may be mediated through blockade of the H1R and the associated activation of hypothalamic AMPK. Abstract »  
Peter Stern
Sci. STKE 6 March 2007: tw79.
Rats that tend to abuse cocaine have lower dopamine receptor availability even before drug exposure, suggesting that this trait is preexisting and not a result of drug abuse. Abstract »  
Nancy R. Gough
Sci. STKE 6 March 2007: tw80.
A mitogen-activated protein kinase cascade appears critical to maintaining the one-cell spacing of stomata in plant leaves. Abstract »  
Stephen Simpson
Sci. STKE 6 March 2007: tw81.
A kinase activated in response to viral infection unexpectedly acts directly on a transcription factor for antiviral genes. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882