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Cover Figure

COVER This week features a Perspective on focal adhesions, protein complexes that link the cell interior to the extracellular matrix. The image illustrates a model of focal adhesion proteins functioning as a molecular clutch. [Image: Yu-Li Wang, University of Massachusetts Medical School]

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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882