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Perspectives

Benjamin E. Steinberg and Sergio Grinstein
Sci. STKE 27 March 2007: pe11.
Phagocytic NADPH oxidase contributes to various neutrophil processes including the formation of neutrophil extracellular traps (NETs). Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 27 March 2007: tw98.
Preserving ovarian function may improve the health of aging female mice. Abstract »  
John F. Foley
Sci. STKE 27 March 2007: tw99.
The tumor suppressor p53 induces cardiac dysfunction through the inhibition of angiogenesis. Abstract »  
Nancy R. Gough
Sci. STKE 27 March 2007: tw100.
The H+ pump and membrane voltage play crucial roles in Xenopus tail regeneration. Abstract »  
Elizabeth M. Adler
Sci. STKE 27 March 2007: tw101.
Association of Nod2 with cytoskeletal structures may represent a sequestration mechanism that allows its ready mobilization to activate NF-{kappa}B. Abstract »  
John F. Foley
Sci. STKE 27 March 2007: tw102.
A deubiquitinylase component of the COP9 signalosome stabilizes I{kappa}B{alpha}, thereby regulating NF-{kappa}B activation. Abstract »  
Elizabeth M. Adler
Sci. STKE 27 March 2007: tw103.
The cytokine formerly known as T cell growth factor appears to attenuate the differentiation of T helper 17 (Th17) cells. Abstract »  
Stephen Simpson
Sci. STKE 27 March 2007: tw104.
Upon antigen binding, immune cells generate pathogen-fighting cells from daughters arising close to the antigen and memory cells from daughters away from it. Abstract »  
Nancy R. Gough
Sci. STKE 27 March 2007: tw105.
Activation of the Hedgehog pathway is one way oxysterols promote osteoblast differentiation. Abstract »  
Pamela J. Hines
Sci. STKE 27 March 2007: tw106.
The cell surface receptor for an important growth regulator in plants binds to its ligand with high affinity and activates downstream targets. Abstract »  
Nancy R. Gough
Sci. STKE 27 March 2007: tw107.
SCOP cleavage by calpain allows activation of mitogen-activated protein kinases and gene expression that promotes memory formation. Abstract »  
L. Bryan Ray
Sci. STKE 27 March 2007: tw108.
A genetic circuit for bacterial cell differentiation exhibits a surprisingly varied repertoire of dynamic responses that depend on the amount of noise in the component biochemical reactions. Abstract »  
Gilbert Chin
Sci. STKE 27 March 2007: tw109.
The crystal structure of a key metabolic regulator reveals how it senses the ratio of ATP to AMP, initiating feedback processes to optimize ATP levels in the cell. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882