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Editorial Guides

Elizabeth M. Adler and Nancy R. Gough
Sci. STKE 10 April 2007: eg2.
Recent research on cancer cell pathophysiology provides reasons to be hopeful about development of novel therapies. Abstract »   Full Text »   PDF »  

 

Perspectives

Karlheinz Friedrich, Ottmar Janssen, and Ralf Hass
Sci. STKE 10 April 2007: pe13.
The most recent meeting of the Signal Transduction Society highlighted the translation of signaling research into advances in the cancer clinic. Abstract »   Full Text »   PDF »  
James G. Pan and Tak W. Mak
Sci. STKE 10 April 2007: pe14.
Could targeted therapies directed against aerobic metabolism represent a viable approach to treating cancer? Abstract »   Full Text »   PDF »  

 

Reviews

Coralie A. Carothers Carraway and Kermit L. Carraway
Sci. STKE 10 April 2007: re3.
Can oncogenesis occur by co-opting normal physiological responses to epithelial damage? Gloss »   Abstract »   Full Text »   PDF »  

 

Editors' Choice

L. Bryan Ray
Sci. STKE 10 April 2007: tw120.
Glial cells in the brain sense Na+ concentrations and signal through lactate secretion to neighboring neurons. Abstract »  
L. Bryan Ray
Sci. STKE 10 April 2007: tw121.
A yeast enzyme is identified that synthesizes the inositol pyrophosphate IP6. Abstract »  
Nancy R. Gough
Sci. STKE 10 April 2007: tw122.
Glycosylation of growth factor receptors controls their duration at the cell surface and may explain the proliferative versus growth-arresting responses to these receptors. Abstract »  
Nancy R. Gough
Sci. STKE 10 April 2007: tw123.
Release of ACBD3 by Golgi fragmentation during mitosis may provide a mechanism for coupling Numb functions to the cell cycle. Abstract »  
Elizabeth M. Adler
Sci. STKE 10 April 2007: tw124.
Degradation of the Ubc7 E2 ubiquitin ligase depends on autoubiquitination on a cysteine residue. Abstract »  
John F. Foley
Sci. STKE 10 April 2007: tw125.
Regulation of estrogen receptor {alpha} activity may occur through the ubiquitin ligase activity of BRCA1. Abstract »  
John F. Foley
Sci. STKE 10 April 2007: tw126.
The tumor suppressor HRSL3 induces apoptosis in an ovarian cancer cell line by inhibiting protein phosphatase 2A activity. Abstract »  
John F. Foley
Sci. STKE 10 April 2007: tw127.
Lysophosphatidic acid-mediated inhibition of interleukin-13 signaling could modulate airway responsiveness in asthma. Abstract »  
Paula A. Kiberstis
Sci. STKE 10 April 2007: tw128.
Small dogs are small because they carry a particular allele of the gene encoding insulin-like growth factor 1. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882