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Perspectives

Arthur J. Sytkowski
Sci. STKE 17 July 2007: pe38.
Clinical studies have raised the possibility of a growth-promoting action of Epo on cancer cells. Abstract »   Full Text »   PDF »  

 

Editors' Choice

L. Bryan Ray
Sci. STKE 17 July 2007: tw248.
Distinct subsets of the available interaction domains of a scaffolding protein are recruited in muscle and heart to support tissue-specific developmental programs. Abstract »  
John F. Foley
Sci. STKE 17 July 2007: tw249.
Cytokines better known for controlling T cell differentiation are now implicated in mammary epithelial cell differentiation. Abstract »  
Stephen Simpson
Sci. STKE 17 July 2007: tw250.
The decision to promote distinct immune cells, which either prevent or promote inflammation, is regulated by the vitamin A metabolite retinoic acid. Abstract »  
L. Bryan Ray
Sci. STKE 17 July 2007: tw251.
Excreted thioredoxin appears to modulate receptor signaling. Abstract »  
Elizabeth M. Adler
Sci. STKE 17 July 2007: tw252.
CD6 binds pathogen-associated molecular patterns present on bacteria and may prove useful in the therapy of septic shock. Abstract »  
Nancy R. Gough
Sci. STKE 17 July 2007: tw253.
An ATP receptor on the contractile vacuole is needed for osmoregulation in Dictyostelium discoideum. Abstract »  
John F. Foley
Sci. STKE 17 July 2007: tw254.
CIP2A promotes cellular transformation by blocking PP2A-mediated dephosphorylation of c-Myc. Abstract »  
Valda Vinson
Sci. STKE 17 July 2007: tw255.
Structural and functional studies suggest that mutations in two noncatalytic domains of an important kinase can cause cancer by releasing an inhibitor. Abstract »  
Beverly A. Purnell
Sci. STKE 17 July 2007: tw256.
A repetitive DNA segment in the growth hormone gene is transcribed during pituitary development and establishes chromatin structure for activation of gene transcription. Abstract »  
Guy Riddihough
Sci. STKE 17 July 2007: tw257.
The close association of two sister chromatids can occur as a result of DNA damage and does not require simultaneous DNA replication, as previously thought. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882