Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Subscribe

Page Content

Search Science Signaling


Contents

For all checked items

 

Editorial Guides

John F. Foley and Elizabeth M. Adler
Sci. STKE 7 August 2007: eg7.
Three articles highlight signals controlling T cell fate, T cell responsiveness, and the response to cytokines secreted by T cells. Abstract »   Full Text »   PDF »  

 

Perspectives

Edgar Serfling, Friederike Berberich-Siebelt, and Andris Avots
Sci. STKE 7 August 2007: pe42.
The NFAT transcription factors may hold the key to T cell memory. Abstract »   Full Text »   PDF »  
Binks W. Wattenberg and Daniel M. Raben
Sci. STKE 7 August 2007: pe43.
Diacylglycerol kinases are key negative regulators of immune responses in a broad array of cells. Abstract »   Full Text »   PDF »  

 

Reviews

Anders Lindén
Sci. STKE 7 August 2007: re4.
Act1 may play a role in local inflammatory responses mediated by IL-17. Gloss »   Abstract »   Full Text »   PDF »  

 

Editors' Choice

Nancy R. Gough
Sci. STKE 7 August 2007: tw278.
Milk from mothers deficient in PPAR{gamma}, a transcription factor that regulates lipid biosynthesis, is high in inflammatory lipids and toxic to nursing pups. Abstract »  
Elizabeth M. Adler
Sci. STKE 7 August 2007: tw279.
Membrane microdomains that act as "nanoswitches" may be crucial for high-fidelity signal transduction. Abstract »  
John F. Foley
Sci. STKE 7 August 2007: tw280.
TNF-{alpha} suppresses the expression of clock genes, leading to the fatigue associated with microbial infections. Abstract »  
Pamela J. Hines
Sci. STKE 7 August 2007: tw281.
In plants, a female-specific kinase senses the arrival of the pollen tube, setting the stage for the next stages of fertilization and potentially controlling reproductive compatibility. Abstract »  
Elizabeth M. Adler
Sci. STKE 7 August 2007: tw282.
Slit not only coordinates axonal guidance and adhesion but also stimulates formation of a complex that releases beta-catenin from N-cadherin, enabling changes in gene transcription. Abstract »  
John F. Foley
Sci. STKE 7 August 2007: tw283.
Wnt signaling and Cdc42 cooperate to reorient the cell’s organelles. Abstract »  
L. Bryan Ray
Sci. STKE 7 August 2007: tw284.
Identifying the genetic and protein targets of the insulin signaling pathway in C. elegans reveals mechanisms that potentially control the aging process. Abstract »  
Stephen J. Simpson
Sci. STKE 7 August 2007: tw285.
Immune cells that reside in endothelial tissues remain attached to the walls of blood vessels and survey for signs of damage and infection. Abstract »  
Stephen J. Simpson
Sci. STKE 7 August 2007: tw286.
In mice, the innate immune response to microbes is controlled by blocking degradation of a transcriptional inhibitor, dampening an otherwise potentially dangerous response. Abstract »  
Valda J. Vinson
Sci. STKE 7 August 2007: tw287.
Fluorescent labeling of cysteines in living cells reveals how mechanical stress can cause force-induced conformational changes in cellular proteins. Abstract »  
For all checked items

To Advertise     Find Products


Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882