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Krit Kitisin, Tapas Saha, Tiffany Blake, Nady Golestaneh, Merlyn Deng, Christine Kim, Yi Tang, Kirti Shetty, Bibhuti Mishra, and Lopa Mishra
Sci. Signal. 14 August 2007: cm1.
This pathway highlights the role of the TGF-beta signaling pathway in key aspects of mammalian development. Abstract »   Full Text »   PDF »   Supplemental Table »   Pathway »  

 

Perspectives

Daniel S. McGehee
Sci. STKE 14 August 2007: pe44.
Nicotine's modulation of synaptic plasticity in prefrontal cortex may contribute to its effects on memory and reward circuitry. Abstract »   Full Text »   PDF »  

 

Editors' Choice

Nancy R. Gough
Sci. STKE 14 August 2007: tw288.
Osteoblasts release osteocalcin to stimulate metabolism. Abstract »  
Elizabeth M. Adler
Sci. STKE 14 August 2007: tw289.
The gastrin-releasing peptide receptor mediates a central pathway for itch sensation. Abstract »  
Nancy R. Gough
Sci. STKE 14 August 2007: tw290.
A common inflammatory skin disorder is caused by aberrant processing of cathelicidin antimicrobial peptides. Abstract »  
Elizabeth M. Adler
Sci. STKE 14 August 2007: tw291.
Jasmonate signaling stimulates the degradation of JAZ-family transcriptional repressors, enabling the transcriptional activation of target genes. Abstract »  
Nancy R. Gough
Sci. STKE 14 August 2007: tw292.
By inactivating the tuberous sclerosis complex (TSC), this kinase downstream of inflammatory cytokines stimulates the mTOR pathway and angiogenesis. Abstract »  
John F. Foley
Sci. STKE 14 August 2007: tw293.
PLC-beta-mediated intracellular Ca2+ flux contributes to SDF-1{alpha}-induced T cell chemotaxis. Abstract »  
John F. Foley
Sci. STKE 14 August 2007: tw294.
Two studies identify the second subunit of the IL-33 receptor and demonstrate the role of IL-33 in mast cells. Abstract »  
L. Bryan Ray
Sci. STKE 14 August 2007: tw295.
In older mice, overexpression of a signaling pathway may inhibit muscle regeneration by accelerating stem cell senescence while decreasing their proliferation. Abstract »  
Valda J. Vinson
Sci. STKE 14 August 2007: tw296.
Molecular dynamics simulations of a Na+/H+ antiporter allow the proposal of an atomically detailed model for the mechanism of ion transport, pH regulation, and cation selectivity. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882