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Perspectives

Jerome A. Langer
Sci. STKE 25 September 2007: pe53.
Variant IFN-{alpha} proteins with novel activity profiles may translate into better therapeutics and provide mechanistic insights. Abstract »   Full Text »   PDF »  
Jonathan M. W. Slack
Sci. STKE 25 September 2007: pe54.
A proton pump may play a critical role in Xenopus tadpole tail regeneration. Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 25 September 2007: tw341.
The calcium increase at fertilization independently activates kinase and phosphatase activity. Abstract »  
L. Bryan Ray
Sci. STKE 25 September 2007: tw342.
A microRNA-mediated feedback loop contributes to regulation of insect metamorphosis. Abstract »  
Nancy R. Gough
Sci. STKE 25 September 2007: tw343.
Taste receptors appear to play a role in sensing sugar in the intestinal tract. Abstract »  
John F. Foley
Sci. STKE 25 September 2007: tw344.
A family of ubiquitin ligases targets SUMOylated proteins. Abstract »  
Elizabeth M. Adler
Sci. STKE 25 September 2007: tw345.
Acid-sensing ion channels exist as trimers that may be gated through movement of an extracellular "thumb." Abstract »  
Gilbert Chin
Sci. STKE 25 September 2007: tw346.
The crystal structure of a bacterial membrane transporter reveals that it uses an unusual two-site, zinc-for-proton exchange mechanism. Abstract »  
Phil Szuromi
Sci. STKE 25 September 2007: tw347.
Free-solution, label-free molecular interactions can be investigated using back-scattering interferometry (BSI), which allows quantification of Kd values ranging from micromolar to picomolar using minuscule quantities of the binding pairs. Abstract »  
Nancy R. Gough
Sci. STKE 25 September 2007: tw348.
Metastatic cells appear to use the epidermal growth factor receptor ErbB1 to migrate through an electric field. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882