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Perspectives

Kimberly Gerrow and Alaa El-Husseini
Sci. STKE 16 October 2007: pe56.
Proteins derived from both sides of the synapse contribute to glutamate receptor clustering. Abstract »   Full Text »   PDF »  
Robert A. Schlegel and Patrick Williamson
Sci. STKE 16 October 2007: pe57.
The receptor on phagocytes that recognizes phosphatidylserine on apoptotic cells remains elusive. Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 16 October 2007: tw368.
The scaffolding protein INAD plays a dynamic role in Drosophila phototransduction. Abstract »  
Elizabeth M. Adler
Sci. STKE 16 October 2007: tw369.
Acetylation plays a key role in type I interferon receptor signaling. Abstract »  
Nancy R. Gough
Sci. STKE 16 October 2007: tw370.
Although phosphorylated cofilin is inactive for its role as an actin-depolymerizing factor, it does have a role in mediating G protein-coupled receptor stimulation of phospholipase D. Abstract »  
John F. Foley
Sci. STKE 16 October 2007: tw371.
Adrenaline and noradrenaline released from phagocytes make inflammation worse. Abstract »  
L. Bryan Ray
Sci. STKE 16 October 2007: tw372.
Endothelial cells that line the blood vessels appear to stiffen in response to small changes in sodium concentration. Abstract »  
Elizabeth M. Adler
Sci. STKE 16 October 2007: tw373.
The cholesterol metabolite 27-hydroxycholesterol may act as an endogenous SERM. Abstract »  
Nancy R. Gough
Sci. STKE 16 October 2007: tw374.
A genome-wide screen in Caenorhabditis elegans reveals components of a mitochondrial unfolded protein response pathway. Abstract »  
John F. Foley
Sci. STKE 16 October 2007: tw375.
Amyloid precursor protein regulates apolipoprotein E and cholesterol metabolism in the brain. Abstract »  
Valda J. Vinson
Sci. STKE 16 October 2007: tw376.
The structure of the catalytic subunit of cyclic AMP-dependent protein kinase bound to a regulatory subunit reveals how this enzyme activates two different signaling pathways. Abstract »  
Paula A. Kiberstis
Sci. STKE 16 October 2007: tw377.
In glioblastoma cancer cells, drugs that work by inhibiting receptor tyrosine kinases are more powerful in combination than when administered alone. Abstract »  
Beverly A. Purnell
Sci. STKE 16 October 2007: tw378.
A novel technology to disrupt miRNA-mRNA interactions reveals that some miRNAs may repress antagonistic developmental regulators. Abstract »  
Pamela J. Hines
Sci. STKE 16 October 2007: tw379.
Flowering is triggered only when both light and enough of a particular protein are available in the afternoon, conditions only satisfied during longer days of spring. Abstract »  
Pamela J. Hines
Sci. STKE 16 October 2007: tw380.
Lysophospholipids made in the roots of tomato and potato plants, which grow in association with mycorrhizal fungi, induce genes for phosphate transfer in the fungi. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882