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Perspectives

William Dauer
Sci. STKE 6 November 2007: pe60.
Identification of a new family of neurotrophic factors raises hopes for new therapeutic strategies against Parkinson's disease. Abstract »   Full Text »   PDF »  
Cathleen Frederickson, Christopher J. Frederickson, Wolfgang Maret, Harold Sandstead, Leonard Giblin, and Richard Thompson
Sci. STKE 6 November 2007: pe61.
Zinc researchers are galvanized by new findings and technical advances in the field of ionic zinc signaling. Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 6 November 2007: tw398.
Antibodies directed against PIGF may be useful in cancer therapy. Abstract »  
Nancy R. Gough
Sci. STKE 6 November 2007: tw399.
Full-length and caspase-cleaved forms of the serine-threonine kinase Mst1 inhibit Akt activity. Abstract »  
Elizabeth M. Adler
Sci. STKE 6 November 2007: tw400.
Sig-1Rs act as ligand- and calcium-modulated ER chaperones that modulate ER-mitochondrial signaling. Abstract »  
L. Bryan Ray
Sci. STKE 6 November 2007: tw401.
A quinoxalinedione glutamate receptor antagonist becomes an agonist when the receptor acquires an extra subunit, coupling changes in ligand binding to opening of the channel. Abstract »  
John F. Foley
Sci. STKE 6 November 2007: tw402.
STAT3 connects ephrinB1 to the nucleus. Abstract »  
John F. Foley
Sci. STKE 6 November 2007: tw403.
ATP stimulates action potentials in developing auditory neurons. Abstract »  
Nancy R. Gough
Sci. STKE 6 November 2007: tw404.
Plasmacytoid dendritic cells signal through a cascade very similar to that activated by B cell receptors. Abstract »  
Pamela J. Hines
Sci. STKE 6 November 2007: tw405.
Forelimb regeneration in newts requires concomitant regeneration of the nerve, a necessity that can be circumvented by application of a single protein, nAG. Abstract »  
Paula A. Kiberstis
Sci. STKE 6 November 2007: tw406.
A study of mice identifies a protein that may malfunction in gestational diabetes, a common complication of pregnancy. Abstract »  
Beverly A. Purnell
Sci. STKE 6 November 2007: tw407.
The cycling of three protein components comprising the circadian clock in cyanobacteria is driven by a pattern of sequential phosphorylation that can be described mathematically. Abstract »  
Beverly A. Purnell
Sci. STKE 6 November 2007: tw408.
The ring of gene expression that sweeps across sea urchin embryos is controlled by a regulatory circuit that generates a wave of activation followed by a wave of repression. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882