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Perspectives

Clare H. Faux and John G. Parnavelas
Sci. STKE 13 November 2007: pe62.
Do calcium signals coordinate neuronal migration? Abstract »   Full Text »   PDF »  
Hiroko Sano, Sara Ricardo, and Ruth Lehmann
Sci. STKE 13 November 2007: pe63.
Border cells use multiple mechanisms to move as a collective unit. Abstract »   Full Text »   PDF »  

 

Reviews

Yulia A. Komarova, Dolly Mehta, and Asrar B. Malik
Sci. STKE 13 November 2007: re8.
Inflammatory mediators both disrupt and help repair the endothelial barrier. Gloss »   Abstract »   Full Text »   PDF »  

 

Editors' Choice

Elizabeth M. Adler
Sci. STKE 13 November 2007: tw409.
Calpain cleavage of the integrin beta3 cytoplasmic domain switches the integrin signal to promote cell retraction instead of cell spreading. Abstract »  
Nancy R. Gough
Sci. STKE 13 November 2007: tw410.
By triggering coendocytosis of N-cadherin through a p38 MAPK pathway, arcadlin decreases the number of dendritic spines. Abstract »  
L. Bryan Ray
Sci. STKE 13 November 2007: tw411.
An unusual phosphorylation mechanism appears to regulate a protease that monitors stress in the mitochondria. Abstract »  
Stella M. Hurtley
Sci. STKE 13 November 2007: tw412.
When misfolded proteins accumulate within the endoplasmic reticulum, protective responses are initiated, but prolonged stress ultimately triggers cell death pathways. Abstract »  
John F. Foley
Sci. STKE 13 November 2007: tw413.
Double-negative feedback regulates the oncogenic tyrosine kinase NPM-ALK and STAT5A. Abstract »  
Nancy R. Gough
Sci. STKE 13 November 2007: tw414.
A morphological change limits blood flow to the right side branchial arch artery, leading to its regression. Abstract »  
Elizabeth M. Adler
Sci. STKE 13 November 2007: tw415.
Daily exposure to high-frequency, low-magnitude mechanical signals may attenuate adipocyte production. Abstract »  
John F. Foley
Sci. STKE 13 November 2007: tw416.
TLR4 signaling sensitizes hepatic stellate cells to TGF-beta, thus enhancing fibrogenesis. Abstract »  
Nancy R. Gough
Sci. STKE 13 November 2007: tw417.
Phosphorylation of the Smoothened protein alleviates an intramolecular inhibitory interaction of the cytoplasmic domain, allowing intermolecular interactions to occur. Abstract »  
L. Bryan Ray
Sci. STKE 13 November 2007: tw418.
Nutrients turn on a regulator of cell growth and proliferation by displacing an inhibitor of the regulator’s kinase activity with a small guanosine triphosphatase. Abstract »  
Stella M. Hurtley
Sci. STKE 13 November 2007: tw419.
The bacterium that causes Legionnaires’ disease recruits a host protein that regulates vesicle trafficking by mimicking host-activating proteins. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882