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Editorial Guides

Nancy R. Gough
Sci. STKE 4 December 2007: eg11.
The nucleus is connected to cytoplasmic signaling networks and has its own complex signaling environment. Abstract »   Full Text »   PDF »  



Rafael Alvarez-Gonzalez
Sci. STKE 4 December 2007: pe68.
In response to DNA damage, p53 is modified by poly(ADP-ribose) polymerase-1 (PARP-1) and accumulates in the nucleus. Abstract »   Full Text »   PDF »  
Steven M. Swanson and John J. Kopchick
Sci. STKE 4 December 2007: pe69.
Translocation of the growth hormone receptor to the nucleus is linked with tumorigenesis. Abstract »   Full Text »   PDF »  


Editors' Choice

John F. Foley
Sci. STKE 4 December 2007: tw436.
Ribosomal protein S3 is an essential subunit of NF-{kappa}B complexes that confers selectivity toward target genes. Abstract »  
Elizabeth M. Adler
Sci. STKE 4 December 2007: tw437.
The maturation of GABAergic inhibition--and thereby the onset of ocular dominance plasticity--is regulated by an activity-dependent decrease in polysialic acid. Abstract »   Podcast »  
Elizabeth M. Adler
Sci. STKE 4 December 2007: tw438.
RGS2 decreases coupling between GABAB receptors and GIRK channels, thereby influencing the bidirectional effects of GABAB agonists on activity of ventral tegmental dopamine neurons. Abstract »  
Nancy R. Gough
Sci. STKE 4 December 2007: tw439.
cGMP-dependent protein kinase phosphorylates GluR1-type glutamate receptor subunits and increases their abundance at the cell surface. Abstract »  
L. Bryan Ray
Sci. STKE 4 December 2007: tw440.
Requirements of LTP signaling vary in the developing brain. Abstract »  
Nancy R. Gough
Sci. STKE 4 December 2007: tw441.
Targeting host kinases, such as Akt1, may be an effective strategy to control bacterial infection. Abstract »  
Stephen J. Simpson
Sci. STKE 4 December 2007: tw442.
A pathogen-sensing protein of the innate immune system recognizes the 5'-triphosphate structures of single-stranded RNA present in many bacteria and viruses. Abstract »  
John F. Foley
Sci. STKE 4 December 2007: tw443.
The invasion of one epithelial cell by another provides a nonapoptotic mechanism of cell death, entosis, which is dependent on adherens junction formation. Abstract »  
Pamela J. Hines
Sci. STKE 4 December 2007: tw444.
A protein that forms particularly tight junctions between intestinal or endothelial cells also seals the ends of the myelin wrapping around nerve axons. Abstract »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882