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Editors' Choice

Nancy R. Gough
2 February 2010: ec36.
A fragment specific to Nogo-A is internalized to trigger growth cone collapse. Abstract »  
Wei Wong
2 February 2010: ec37.
Neighboring cells with distinct mutations can cooperate to form invasive tumors. Abstract »  
Kristen Mueller
2 February 2010: ec38.
Microparticles released by platelets contribute to inflammation underlying rheumatoid arthritis. Abstract »  
John F. Foley
2 February 2010: ec39.
T helper 2 (TH2) cells can be induced to adopt both TH1 and TH2 phenotypes in the context of viral infection. Abstract »  
Elizabeth M. Adler
2 February 2010: ec40.
Anthrax toxin stimulates intracellular signaling events to facilitate its entry into the target cell. Abstract »  
Nancy R. Gough
2 February 2010: ec41.
Parasitic worms secrete proteases that when internalized suppress the immune response to promote an anti-inflammatory environment. Abstract »  
Paula A. Kiberstis
2 February 2010: ec42.
Ionizing radiation destroys gastrointestinal epithelial cells by a mechanism that appears to be independent of apoptosis. Abstract »  
Peter R. Stern
2 February 2010: ec43.
Cyclic adenosine monophosphate and cyclic guanosine monophosphate regulate axon formation and exert opposite actions on dendrite formation. Abstract »  
L. Bryan Ray
2 February 2010: ec44.
The energy-sensing kinase AMPK is coupled to hormonal control of metabolism through PKA. Abstract »  



Tomoshige Kino and Annalisa M. VanHook
2 February 2010: pc3.
A noncoding RNA competes with DNA for binding to the glucocorticoid receptor. Abstract »   Full Text »   Podcast »  


Research Articles

Tomoshige Kino, Darrell E. Hurt, Takamasa Ichijo, Nancy Nader, and George P. Chrousos
2 February 2010: ra8.
Gas5 is a noncoding RNA that acts as a decoy glucocorticoid response element to inhibit glucocorticoid-mediated transcription. Editor's Summary »   Abstract »   Full Text »   PDF »   Supplementary Materials »  


Meeting Reports

Darja Obradovic Wagner, Christina Sieber, Raghu Bhushan, Jan H. Börgermann, Daniel Graf, and Petra Knaus
2 February 2010: mr1.
Discussion at a meeting in Berlin, Germany, showed that BMPs have essential functions in organs and tissues besides bone. Abstract »   Full Text »   PDF »  
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Science Signaling. ISSN 1937-9145 (online), 1945-0877 (print). Pre-2008: Science's STKE. ISSN 1525-8882